Technical Papers

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An Investigation of the Effect of Different Plasticizer Systems on the Dry Powder Coating of Acetaminophen Beads with EUDRAGIT E PO Using a Novel Rotor Processor

(PDF, 1.1M)

Utilization of a Novel Rotor-Granulator Powder Layering Technique to Tasted Mask Acetaminophen Pellets with EUDRAGIT E PO

(PDF, 428k)

Processing Changes Monitored During Spheronization and Powder Layering Via Use of a Graphical Imaging Tool

(PDF, 570k)

Coating Process Step Deviations Monitored Via Use Of A Graphical Imaging Tool

(PDF, 451k)

Discussion of Processes Which Utilize Conical Rotor Technology (Spheronization or Spherical Granulation, Powder Layering of Actives or Polymers, Conventional Solution/Suspension Application of Actives or Polymers)

(PDF, 3.65M)

In June 2009, this poster was awarded best-in-show at the 49th Associazione Farmaceutici Industria Symposium in Rimini, Italy.

Optimization of Binder Level in Moisture Activated Dry Granulation (MADG) Using Absorbent Starch to Distribute Moisture

(JPG, 1,100k)

A Novel Process For Applying Methylmethacrylates (MMA) to Multi-Particulates at a High Speed Utilizing a Rotor Processor

(PDF, 863k)

Comparison of Different Methods of Binder Addition on Particle Size and Shape for High-Shear Granulation Processes

(PDF, 297k)

Clear Coated Tablets with High-Solids Aqueous Starch Coating and Minimal Tablet Weight Gain

(PDF, 457k)

Evaluation of a Process to Quickly and Efficiently Apply Dry Polymer to Acetaminophen Beads Using A Rotor Procossor

(PDF, 638k)

A Comparison of a Novel Rotor Processor with a Wurster Processor, Showing the Efficiency, Uniformity and Total Process Time to Apply a Sustained Release Polymer to Acetaminophen Beads

(PDF, 645k)

Rapid Polymetric Coating Technique Using Powder Layering in Rotor-Equipped Fluid Bed

(PDF, 2.0 Meg)

Evaluation of a Novel Rotor Processor to Manufacture Spherical 100 - 300 micron Acetaminophen Beads, Using Two Methods; Spheronization and Powder Layering

(PDF, 679k)

A Comparison of a Novel Rotor Process with a Wurster Processor, Showing the Efficiency, Uniformity and Total Process Time to Manufacture Spherical Omeprazole Beads in the Range of 100-300 Microns

(PDF, 587k)

Particle Characterization Utilizing PAT (Process Analytical Technology) Tools

(PDF, 759k)

Evaluation of a Simple Fluid Bed Dryer Sampler Modification for On-Line Profiling and Endpoint Using Effusivity

(PDF, 101k)

Optimization of Cold Water Starch Granulations Using High Shear Granulating Methods and Capitalizing on the Strength of Fully Pregelantinized Starch Incorporated as a Dry Binder

(PDF, 2.5 Meg)

Application of Thermal Effusivity as a Non-Destructive Method to Evaluate the Impact of Compression Forces

(PDF, 341k)

Impact of Different Roll Sizes on Roller Compactor Granulations

(PDF, 483k)

Top-Drive vs. Bottom-Drive High-Shear Granulation: Dissolution Profiles of Immediate Release Tablets

(PDF, 584k)

Comparison of Flow Properties of Granules Prepared by Top-Drive and Bottom-Drive High-Shear Granulators

(PDF, 392k)

Comparison of Film Coating Process Using Fully Perforated and Partially Perforated Coating Pans

(PDF, 318k)

Comparison of Methods for Determining Particle Size Distribution and Powder Flowability

(PDF, 779k)

Top-Drive vs. Bottom-Drive High-Shear Granulation: Effect on Granule Properties of an Immediate Release Formulation

(PDF, 568k)

Comparison of Wet Granulation Processes Using Top-Drive and Bottom-Drive High-Shear Granulators

(PDF, 590k)

Direct Comparison of Wet-Granulation Processes in a High-Shear Granulator and an Innovative Rotor Processor

(PDF, 576k)

The Change in Particle Size of Immediate Release and Controlled Release Formulations During High-Shear Wet-Granulation Processes

(PDF, 507k)

Comparison of End-Point Determination by Wet-Mass Time, Product Temerature Change, and Power Consumption for Scale-Up of High Shear Granulation of Immediate and Controlled Release Formulations

(PDF, 485k)

The Effect of Load Volume on Particle Size and Temperature Rise of Wet-Granulations in a High-Shear Granulator

(PDF, 675k)

The Effect of Consecutive Batch Processing on Particle Size and Thermal Behavior in a High-Shear Granulator

(PDF, 623k)

The Effect of Consecutive Batch Processing on Particle Size and Thermal Behavior in a High-Shear Granulator - Addendum

(PDF, 1.8 Meg)